One covers a total of 1000m by doing 100m all out sprints, followed by short rests, then repeating each sprints.
The other covers a similar 1000m by running at a constant pace.
Both will derive entirely different physiological responses and benefits despite covering the same distance.
The same idea can be used to explain why not everyone experiences TSA.
Using strong TS for short periods of time, compared to cumulative and frequent usage of low-potency TS over a long period of time can result in remarkably different physiological responses.
Of course, we should compare apples to apples.
One, we can give 2 separate person an equal amount of TS in mass, and have one use them in short bursts separated by a resting period, and the other using them cumulatively and frequently. Until both of them run out of TS. The variable then would then be the periodicity of application. And then we measure the effects. It sounds relatively straightforward, but one big variable we fail to take into account is time. With time, more multitude of factors can creep in for the first person (the one who applies TS in short term). In this situation, time is given for the skin to rest and recover. For the other, little or no time is given for the skin to rest, and hence allowing for the possibility for continual damage on the skin by TS.
Or if we want to measure the results of TS-concentration/potency. Have 2 subjects applying TS of different potencies, at the same periodicity (short bursts with rest time and/or continual application). And measure the results. This would be more conclusive.
When we look at the real world and realise that not everyone who uses TS becomes addicted, we need to dig deeper and find out why TSA occurs for the select few.
Using TS increases the possibility to become topically addicted, but not necessarily so, depending on the method/frequency/amount you use. Are you the sprinter or the slow paced jogger? Remember that both have different physiological results.
There are so many TSA sufferers who are so deeply against the usage of TS that they fail to recognise this reality, and they assume that everyone who has eczema and everyone who uses TS need to STOP using them. I can understand why they feel this way (given that I am a TSA sufferer as well). But this is a wrong way to look at things. I cringe when I see fellow TSA people condemn others in their usage of TS. When in the first place, there is so little definitive and confirmed knowledge on TSA in itself.
And once you get the reality right, you will be able to position yourself better to make the necessary changes or further your agenda better.