This moisturizer was prescribed to me by my company’s doctor during my initial onset of eczema. I’ve applied them widely and frequently as my skin was constantly dry and irritated. This has probably started the slippery slope of my steroid addiction.
The effect of aqueous cream BP on the skin barrier in volunteers with a previous history of atopic dermatitis.
The abstract as posted in the site:
Background The emollient aqueous cream BP is frequently used for the treatment of atopic dermatitis (AD), yet it is associated with a high rate of adverse cutaneous reactions. It contains the harsh anionic surfactant sodium lauryl sulphate, a known negative environmental factor associated with the exacerbation of AD.
Objectives To investigate the effect of aqueous cream BP on stratum corneum (SC) integrity and skin barrier function in volunteers with a predisposition to a defective skin barrier.
Methods Thirteen volunteers with a previous history of AD (no symptoms for 6 months) applied aqueous cream BP twice daily to the volar side of one forearm for 4 weeks. The other forearm was left untreated as a control. Permeability barrier function and SC integrity were determined before and after treatment by measuring transepidermal water loss (TEWL) in conjunction with tape-stripping. For comparison, 13 volunteers with current AD were recruited for assessment, without treatment, of SC integrity and skin barrier function at unaffected sites.
Results Topical application of aqueous cream BP resulted in significant elevation of baseline TEWL and a concomitant decrease in SC integrity. Measurements made after no treatment in volunteers with current AD, at unaffected sites, suggest that application of aqueous cream BP negatively affects the skin barrier towards the damaged state associated with onset of flares of the disease.
Conclusions Aqueous cream BP used as a leave-on emollient caused severe damage to the skin barrier in volunteers with a previous history of AD. Aqueous cream BP should not be used as a leave-on emollient in patients with AD.
Thoughts: I’ve switched countless moisturizers over the course of my treatment. On hindsight, there were those that irritated the hell out of my skin, and there were some that is comforting and soothing. But that is all to it. My skin was just perennially bad during my periods of moisturizing. There were limited improvements, then back to square one in terms of flaring and oozing.
Upon stopping them, I feel the great difference in terms of rate of healing.
The interesting thing about researching pubmed articles on moisturizing is that there are countless articles concluding that moisturizing is good for AD. How does one reconcile this with one’s personal experience?
My opinion: just try out the recommendations yourself. You are your own guinea pig and you make your own conclusions based on your real experience. You will be better off with the new knowledge gained thru this experience.